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iRhom2: An Emerging Adaptor Regulating Immunity and Disease

The rhomboid family are evolutionary conserved intramembrane proteases. Their inactive members, iRhom in Drosophila melanogaster and iRhom1 and iRhom2 in mammals, lack the catalytic center and are hence labelled “inactive” rhomboid family members. In mammals, both iRhoms are involved in maturation a...

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Detalles Bibliográficos
Autores principales: Al-Salihi, Mazin A., Lang, Philipp A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7554728/
https://www.ncbi.nlm.nih.gov/pubmed/32911849
http://dx.doi.org/10.3390/ijms21186570