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Retinal Pigment Epithelial Cells Derived from Induced Pluripotent Stem (iPS) Cells Suppress or Activate T Cells via Costimulatory Signals

Human retinal pigment epithelial (RPE) cells derived from induced pluripotent stem (iPS) cells have immunosuppressive properties. However, RPE cells are also known as immunogenic cells, and they have major histocompatibility complex expression and produce inflammatory proteins, and thus experience i...

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Detalles Bibliográficos
Autores principales: Sugita, Sunao, Futatsugi, Yoko, Ishida, Masaaki, Edo, Ayaka, Takahashi, Masayo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7554762/
https://www.ncbi.nlm.nih.gov/pubmed/32899567
http://dx.doi.org/10.3390/ijms21186507