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The Impact of Genetic Polymorphisms in Organic Cation Transporters on Renal Drug Disposition

A considerable number of drugs and/or their metabolites are excreted by the kidneys through glomerular filtration and active renal tubule secretion via transporter proteins. Uptake transporters in the proximal tubule are part of the solute carrier (SLC) superfamily, and include the organic cation tr...

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Detalles Bibliográficos
Autores principales: Zazuli, Zulfan, Duin, Naut J. C. B., Jansen, Katja, Vijverberg, Susanne J. H., Maitland-van der Zee, Anke H., Masereeuw, Rosalinde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7554776/
https://www.ncbi.nlm.nih.gov/pubmed/32927790
http://dx.doi.org/10.3390/ijms21186627