Cargando…

Agonist Binding and G Protein Coupling in Histamine H(2) Receptor: A Molecular Dynamics Study

The histamine H [Formula: see text] receptor (H(2)R) plays an important role in the regulation of gastric acid secretion. Therefore, it is a main drug target for the treatment of gastroesophageal reflux or peptic ulcer disease. However, there is as of yet no 3D-structural information available hampe...

Descripción completa

Detalles Bibliográficos
Autores principales: Conrad, Marcus, Söldner, Christian A., Miao, Yinglong, Sticht, Heinrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7554837/
https://www.ncbi.nlm.nih.gov/pubmed/32932742
http://dx.doi.org/10.3390/ijms21186693