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Fingolimod (FTY720) Preserves High Energy Phosphates and Improves Cardiac Function in Heterotopic Heart Transplantation Model

During heart transplantation, donor heart leads to reduced oxygen supply resulting in low level of high energy phosphate (HEP) reserves in cardiomyocyte. Lower HEP is one of the underlying reasons of cell death due to ischemia. In this study we investigated the role of Fingolimod (FTY720) in heart t...

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Detalles Bibliográficos
Autores principales: Ahmed, Naseer, Farooq, Javeria, Sadiq, Soban, Meo, Sultan Ayoub, Jan, Azam, Cheema, Faisal H., Faggian, Giuseppe, Rungatscher, Alessio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7554839/
https://www.ncbi.nlm.nih.gov/pubmed/32911595
http://dx.doi.org/10.3390/ijms21186548