Cinobufagin Suppresses Melanoma Cell Growth by Inhibiting LEF1

Constitutive activation of the β-catenin dependent canonical Wnt signaling pathway, which enhances tumor growth and progression in multiple types of cancer, is commonly observed in melanoma. LEF1 activates β-catenin/TCF4 transcriptional activity, promoting tumor growth and progression. Although seve...

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Detalles Bibliográficos
Autores principales: Kim, Geon-Hee, Fang, Xue-Quan, Lim, Woo-Jin, Park, Jooho, Kang, Tae-Bong, Kim, Ji Hyung, Lim, Ji-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7554883/
https://www.ncbi.nlm.nih.gov/pubmed/32933177
http://dx.doi.org/10.3390/ijms21186706

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7554883/
https://www.ncbi.nlm.nih.gov/pubmed/32933177
http://dx.doi.org/10.3390/ijms21186706

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