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Cinobufagin Suppresses Melanoma Cell Growth by Inhibiting LEF1

Constitutive activation of the β-catenin dependent canonical Wnt signaling pathway, which enhances tumor growth and progression in multiple types of cancer, is commonly observed in melanoma. LEF1 activates β-catenin/TCF4 transcriptional activity, promoting tumor growth and progression. Although seve...

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Detalles Bibliográficos
Autores principales:	Kim, Geon-Hee, Fang, Xue-Quan, Lim, Woo-Jin, Park, Jooho, Kang, Tae-Bong, Kim, Ji Hyung, Lim, Ji-Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7554883/ https://www.ncbi.nlm.nih.gov/pubmed/32933177 http://dx.doi.org/10.3390/ijms21186706

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