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Restraint Stress Alters Expression of Glucocorticoid Bioavailability Mediators, Suppresses Nrf2, and Promotes Oxidative Stress in Liver Tissue

Hepatic glutathione synthesis and antioxidant protection are critically important for efficient detoxification processes in response to metabolic challenges. However, this biosynthetic pathway, regulated by nuclear factor (erythroid-derived 2)-like 2 (Nrf2), previously demonstrated paradoxical repre...

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Detalles Bibliográficos
Autores principales: Chen, Hsiao-Jou Cortina, Yip, Tsz, Lee, Johnny K., Juliani, Juliani, Sernia, Conrad, Hill, Andrew F., Lavidis, Nickolas A., Spiers, Jereme G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7554900/
https://www.ncbi.nlm.nih.gov/pubmed/32932938
http://dx.doi.org/10.3390/antiox9090853