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Maternal N-Acetylcysteine Therapy Prevents Hypertension in Spontaneously Hypertensive Rat Offspring: Implications of Hydrogen Sulfide-Generating Pathway and Gut Microbiota

Hypertension can come from early life. N-acetylcysteine (NAC), a hydrogen sulfide (H(2)S) precursor as well as an antioxidant, has antihypertensive effect. We investigated whether maternal NAC therapy can protect spontaneously hypertensive rats (SHR) male offspring against hypertension. The pregnant...

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Detalles Bibliográficos
Autores principales: Hsu, Chien-Ning, Hou, Chih-Yao, Chang-Chien, Guo-Ping, Lin, Sufan, Tain, You-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7554905/
https://www.ncbi.nlm.nih.gov/pubmed/32933169
http://dx.doi.org/10.3390/antiox9090856