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Understanding the Interaction Modes and Reactivity of Trimedoxime toward MmAChE Inhibited by Nerve Agents: Theoretical and Experimental Aspects

Organophosphorus (OP) compounds are used as both chemical weapons and pesticides. However, these agents are very dangerous and toxic to humans, animals, and the environment. Thus, investigations with reactivators have been deeply developed in order to design new antidotes with better efficiency, as...

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Detalles Bibliográficos
Autores principales: de Castro, Alexandre A., Polisel, Daniel A., Pereira, Bruna T. L., da Cunha, Elaine F. F., Kuca, Kamil, Nepovimova, Eugenie, Ramalho, Teodorico C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7554915/
https://www.ncbi.nlm.nih.gov/pubmed/32899591
http://dx.doi.org/10.3390/ijms21186510