Resveratrol Pretreatment Ameliorates Concanavalin A-Induced Advanced Renal Glomerulosclerosis in Aged Mice through Upregulation of Sirtuin 1-Mediated Klotho Expression

Aging kidneys are characterized by an increased vulnerability to glomerulosclerosis and a measurable decline in renal function. Evidence suggests that renal and systemic klotho and sirtuin 1 (SIRT1) deficiencies worsen kidney damage induced by exogenous stresses. The aim of this study was to explore...

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Detalles Bibliográficos
Autores principales: Chen, Chin-Chang, Chang, Zi-Yu, Tsai, Fuu-Jen, Chen, Shih-Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7554923/
https://www.ncbi.nlm.nih.gov/pubmed/32942691
http://dx.doi.org/10.3390/ijms21186766

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7554923/
https://www.ncbi.nlm.nih.gov/pubmed/32942691
http://dx.doi.org/10.3390/ijms21186766

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