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Epigenetic Scanning of KEAP1 CpG Sites Uncovers New Molecular-Driven Patterns in Lung Adeno and Squamous Cell Carcinomas

Background: The KEAP1/NRF2 (Kelch-like ECH-associated protein 1/nuclear factor erythroid 2–related factor 2) pathway modulates detoxification processes and participates in the resistance of solid tumors to therapy. Scientific evidence about the presence of genetic and epigenetic abnormalities of the...

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Detalles Bibliográficos
Autores principales: Fabrizio, Federico Pio, Mazza, Tommaso, Castellana, Stefano, Sparaneo, Angelo, Muscarella, Lucia Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7554999/
https://www.ncbi.nlm.nih.gov/pubmed/32971994
http://dx.doi.org/10.3390/antiox9090904