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Epigenetic Scanning of KEAP1 CpG Sites Uncovers New Molecular-Driven Patterns in Lung Adeno and Squamous Cell Carcinomas
Background: The KEAP1/NRF2 (Kelch-like ECH-associated protein 1/nuclear factor erythroid 2–related factor 2) pathway modulates detoxification processes and participates in the resistance of solid tumors to therapy. Scientific evidence about the presence of genetic and epigenetic abnormalities of the...
Autores principales: | Fabrizio, Federico Pio, Mazza, Tommaso, Castellana, Stefano, Sparaneo, Angelo, Muscarella, Lucia Anna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7554999/ https://www.ncbi.nlm.nih.gov/pubmed/32971994 http://dx.doi.org/10.3390/antiox9090904 |
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