Semaphorin4A-Plexin D1 Axis Induces Th2 and Th17 While Represses Th1 Skewing in an Autocrine Manner

Semaphorin (Sema)4A is a transmembrane glycoprotein that is elevated in several autoimmune diseases such as systemic sclerosis, rheumatoid arthritis and multiple sclerosis. Sema4A has a key role in the regulation of Thelper Th1 and Th2 differentiation and we recently demonstrated that CD4(+) T cell...

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Detalles Bibliográficos
Autores principales: Carvalheiro, Tiago, Rafael-Vidal, Carlos, Malvar-Fernandez, Beatriz, Lopes, Ana P., Pego-Reigosa, Jose M., Radstake, Timothy R. D. J., Garcia, Samuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555002/
https://www.ncbi.nlm.nih.gov/pubmed/32971928
http://dx.doi.org/10.3390/ijms21186965

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555002/
https://www.ncbi.nlm.nih.gov/pubmed/32971928
http://dx.doi.org/10.3390/ijms21186965

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