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Agent-Based Modeling of T Cell Receptor Cooperativity

Immunological synapse (IS) formation is a key event during antigen recognition by T cells. Recent experimental evidence suggests that the affinity between T cell receptors (TCRs) and antigen is actively modulated during the early steps of TCR signaling. In this work, we used an agent-based model to...

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Detalles Bibliográficos
Autores principales: Siokis, Anastasios, Robert, Philippe A., Meyer-Hermann, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555007/
https://www.ncbi.nlm.nih.gov/pubmed/32899840
http://dx.doi.org/10.3390/ijms21186473