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Aldehyde Dehydrogenase 2 Ameliorates Chronic Alcohol Consumption-Induced Atrial Fibrillation through Detoxification of 4-HNE

Aldehyde dehydrogenase 2 (ALDH2) is an enzyme that detoxifies reactive oxygen species (ROS)-generated aldehyde adducts such as 4-hydroxy-trans-2-nonenal (4-HNE). Previous meta-analyses have shown an increase in the risk of atrial fibrillation (AF) in patients with chronic alcohol consumption. ALDH2*...

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Detalles Bibliográficos
Autores principales: Hsu, Lung-An, Tsai, Feng-Chun, Yeh, Yung-Hsin, Chang, Chi-Jen, Kuo, Chi-Tai, Chen, Wei-Jan, Tsai, Hsin-Yi, Chang, Gwo-Jyh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555032/
https://www.ncbi.nlm.nih.gov/pubmed/32932651
http://dx.doi.org/10.3390/ijms21186678