Effects of IGF-1 on Proliferation, Angiogenesis, Tumor Stem Cell Populations and Activation of AKT and Hedgehog Pathways in Oral Squamous Cell Carcinoma

(1) Background: Activation of the PI3K-AKT pathway controls most hallmarks of cancer, and the hedgehog (HH) pathway has been associated with oral squamous cell carcinoma (OSCC) development and progression. We hypothesized that fibroblast-derived insulin-like growth factor-1 (IGF-1) acts in oral squa...

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Detalles Bibliográficos
Autores principales: Ferreira Mendes, Jéssica Mariane, de Faro Valverde, Ludmila, Torres Andion Vidal, Manuela, Paredes, Bruno Diaz, Coelho, Paulo, Allahdadi, Kyan James, Coletta, Ricardo Della, Souza, Bruno Solano de Freitas, Rocha, Clarissa Araújo Gurgel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555130/
https://www.ncbi.nlm.nih.gov/pubmed/32899449
http://dx.doi.org/10.3390/ijms21186487

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555130/
https://www.ncbi.nlm.nih.gov/pubmed/32899449
http://dx.doi.org/10.3390/ijms21186487

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