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Pharmacokinetics of Repeated Oral Dosing with Coenzyme Q10 in Cavalier King Charles Spaniels with Myxomatous Mitral Valve Disease

Coenzyme Q10 (Q10) is a mitochondrial cofactor and an antioxidant with the potential to combat oxidative stress in heart failure. This study aims to determine the pharmacokinetics of repeated oral dosing of Q10 in Cavalier King Charles Spaniels (CKCS) with spontaneous myxomatous mitral valve disease...

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Detalles Bibliográficos
Autores principales: Christiansen, Liselotte B., Morsing, Malene K., Reimann, Maria Josefine, Martinussen, Torben, Birlie, Zita, Schou-Pedersen, Anne Marie V., Lykkesfeldt, Jens, Olsen, Lisbeth H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555137/
https://www.ncbi.nlm.nih.gov/pubmed/32899633
http://dx.doi.org/10.3390/antiox9090827