Cargando…

Pharmacokinetics of Repeated Oral Dosing with Coenzyme Q10 in Cavalier King Charles Spaniels with Myxomatous Mitral Valve Disease

Coenzyme Q10 (Q10) is a mitochondrial cofactor and an antioxidant with the potential to combat oxidative stress in heart failure. This study aims to determine the pharmacokinetics of repeated oral dosing of Q10 in Cavalier King Charles Spaniels (CKCS) with spontaneous myxomatous mitral valve disease...

Descripción completa

Detalles Bibliográficos
Autores principales:	Christiansen, Liselotte B., Morsing, Malene K., Reimann, Maria Josefine, Martinussen, Torben, Birlie, Zita, Schou-Pedersen, Anne Marie V., Lykkesfeldt, Jens, Olsen, Lisbeth H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555137/ https://www.ncbi.nlm.nih.gov/pubmed/32899633 http://dx.doi.org/10.3390/antiox9090827

Ejemplares similares

Depleted Myocardial Coenzyme Q10 in Cavalier King Charles Spaniels with Congestive Heart Failure Due to Myxomatous Mitral Valve Disease
por: Christiansen, Liselotte B., et al.
Publicado: (2021)

Polymorphisms in the serotonin transporter gene and circulating concentrations of neurotransmitters in Cavalier King Charles Spaniels with myxomatous mitral valve disease
por: Reimann, Maria J., et al.
Publicado: (2021)

Breeding Restrictions Decrease the Prevalence of Myxomatous Mitral Valve Disease in Cavalier King Charles Spaniels over an 8‐ to 10‐Year Period
por: Birkegård, A.C., et al.
Publicado: (2016)

A Genomic Study of Myxomatous Mitral Valve Disease in Cavalier King Charles Spaniels
por: Bionda, Arianna, et al.
Publicado: (2020)

Comparative transcriptomic profiling of myxomatous mitral valve disease in the cavalier King Charles spaniel
por: Markby, G. R., et al.
Publicado: (2020)

Myoclonus in older Cavalier King Charles Spaniels
por: Rotter, Carina, et al.
Publicado: (2022)

Genetic Variants at the Nebulette Locus Are Associated with Myxomatous Mitral Valve Disease Severity in Cavalier King Charles Spaniels
por: Mead, Sophie E., et al.
Publicado: (2022)

Evaluation of the Swedish breeding program for cavalier King Charles spaniels
por: Lundin, Tobias, et al.
Publicado: (2010)

Echocardiographic Evaluation of the Mitral Valve in Cavalier King Charles Spaniels
por: Bagardi, Mara, et al.
Publicado: (2020)

Mitral Regurgitation Severity and Left Ventricular Systolic Dimension Predict Survival in Young Cavalier King Charles Spaniels
por: Reimann, M.J., et al.
Publicado: (2017)

Volume reduction of the jugular foramina in Cavalier King Charles Spaniels with syringomyelia
por: Schmidt, Martin Jürgen, et al.
Publicado: (2012)

Morphometric analysis of spinal cord termination in Cavalier King Charles Spaniels
por: Sparks, Courtney R., et al.
Publicado: (2019)

Medical infrared thermal imaging of syringomyelia in the Cavalier King Charles Spaniel
por: Larkin, M., et al.
Publicado: (2020)

Clinical and Echocardiographic Findings in an Aged Population of Cavalier King Charles Spaniels
por: Prieto Ramos, Jorge, et al.
Publicado: (2021)

Assessing the relative importance of health and conformation traits in the cavalier king Charles spaniel
por: Wijnrocx, Katrien, et al.
Publicado: (2018)

Erratum for Morphometric analysis of spinal cord termination in Cavalier King Charles Spaniels
Publicado: (2019)

Mechanical quantitative sensory testing in cavalier King Charles spaniels with and without syringomyelia
por: Hechler, Ashley C., et al.
Publicado: (2020)

Circulating MiR-30b-5p is upregulated in Cavalier King Charles Spaniels affected by early myxomatous mitral valve disease
por: Bagardi, Mara, et al.
Publicado: (2022)

The genetic consequences of dog breed formation—Accumulation of deleterious genetic variation and fixation of mutations associated with myxomatous mitral valve disease in cavalier King Charles spaniels
por: Axelsson, Erik, et al.
Publicado: (2021)

Syringomyelia: determining risk and protective factors in the conformation of the Cavalier King Charles Spaniel dog
por: Mitchell, Thomas J, et al.
Publicado: (2014)

Corpus Callosotomy in 3 Cavalier King Charles Spaniel Dogs with Drug-Resistant Epilepsy
por: Asada, Rikako, et al.
Publicado: (2021)

No impact of polymorphism in the phosphodiesterase 5A gene in Cavalier King Charles Spaniels on pimobendan‐induced inhibition of platelet aggregation response
por: Reimann, Maria J., et al.
Publicado: (2023)

Correction: The genetic consequences of dog breed formation—Accumulation of deleterious genetic variation and fixation of mutations associated with myxomatous mitral valve disease in cavalier King Charles spaniels
por: Axelsson, Erik, et al.
Publicado: (2022)

Pilot study of head conformation changes over time in the Cavalier King Charles spaniel breed
por: Knowler, Susan Penelope, et al.
Publicado: (2019)

Investigation of sensory thresholds in Cavalier King Charles Spaniels with and without Chiari‐like malformations and syringomyelia
por: Sparks, Courtney R., et al.
Publicado: (2018)

Influence of Morphometry on Echocardiographic Measurements in Cavalier King Charles Spaniels: An Inverse Probability Weighting Analysis
por: Bagardi, Mara, et al.
Publicado: (2021)

Ventriculomegaly in Cavalier King Charles Spaniels with Chiari-like malformation: relationship with clinical and imaging findings
por: TIRRITO, Federica, et al.
Publicado: (2022)

Changes over time in craniocerebral morphology and syringomyelia in cavalier King Charles spaniels with Chiari-like malformation
por: Driver, Colin J, et al.
Publicado: (2012)

Medullary Position at the Craniocervical Junction in Mature Cavalier King Charles Spaniels: Relationship with Neurologic Signs and Syringomyelia
por: Cerda‐Gonzalez, S., et al.
Publicado: (2015)

Prevalence of disorders recorded in Cavalier King Charles Spaniels attending primary-care veterinary practices in England
por: Summers, Jennifer F, et al.
Publicado: (2015)

Degenerative Valvular Disease in the Cavalier King Charles Spaniel: Results of the UK Breed Scheme 1991–2010
por: Swift, S., et al.
Publicado: (2017)

Behavioral and clinical signs of Chiari‐like malformation‐associated pain and syringomyelia in Cavalier King Charles spaniels
por: Rusbridge, Clare, et al.
Publicado: (2019)

Association between filum terminale internum length and pain in Cavalier King Charles spaniels with and without syringomyelia
por: Sparks, Courtney R., et al.
Publicado: (2021)

Three-dimensional kinematics of the craniocervical junction of Cavalier King Charles Spaniels compared to Chihuahuas and Labrador retrievers
por: Nickel, Mareike-Kristin, et al.
Publicado: (2023)

Increase in Cerebellar Volume in Cavalier King Charles Spaniels with Chiari-like Malformation and Its Role in the Development of Syringomyelia
por: Shaw, Thomas A., et al.
Publicado: (2012)

Prevalence and Heritability of Symptomatic Syringomyelia in Cavalier King Charles Spaniels and Long‐term Outcome in Symptomatic and Asymptomatic Littermates
por: Thøfner, M.S., et al.
Publicado: (2014)

Low‐Field MRI and Multislice CT for the Detection of Cerebellar (Foramen Magnum) Herniation in Cavalier King Charles Spaniels
por: Kromhout, K., et al.
Publicado: (2014)

Erratum for “Association between filum terminale internum length and pain in Cavalier King Charles spaniels with and without syringomyelia”
Publicado: (2021)

ACADM Frameshift Variant in Cavalier King Charles Spaniels with Medium-Chain Acyl-CoA Dehydrogenase Deficiency
por: Christen, Matthias, et al.
Publicado: (2022)

Diffusion Tensor Imaging in Syringomyelia Secondary to Chiari Malformation in Cavalier King Charles Spaniel—A Preliminary Study
por: Wrzosek, Marcin Adam, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_ep701c1g9g78fneoip7ri75nbs