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Impact of KLF4 on Cell Proliferation and Epithelial Differentiation in the Context of Cystic Fibrosis
Cystic fibrosis (CF) cells display a more cancer-like phenotype vs. non-CF cells. KLF4 overexpression has been described in CF and this transcriptional factor acts as a negative regulator of wt-CFTR. KLF4 is described as exerting its effects in a cell-context-dependent fashion, but it is generally c...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555189/ https://www.ncbi.nlm.nih.gov/pubmed/32937756 http://dx.doi.org/10.3390/ijms21186717 |