The Circadian Hormone Melatonin Inhibits Morphine-Induced Tolerance and Inflammation via the Activation of Antioxidative Enzymes

Opioids are commonly prescribed for clinical pain management; however, dose-escalation, tolerance, dependence, and addiction limit their usability for long-term chronic pain. The associated poor sleep pattern alters the circadian neurobiology, and further compromises the pain management. Here, we ai...

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Detalles Bibliográficos
Autores principales: Chen, Ing-Jung, Yang, Chih-Ping, Lin, Sheng-Hsiung, Lai, Chang-Mei, Wong, Chih-Shung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555201/
https://www.ncbi.nlm.nih.gov/pubmed/32842597
http://dx.doi.org/10.3390/antiox9090780

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555201/
https://www.ncbi.nlm.nih.gov/pubmed/32842597
http://dx.doi.org/10.3390/antiox9090780

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