Cargando…

Morpholino Analogues of Fingolimod as Novel and Selective S1P(1) Ligands with In Vivo Efficacy in a Mouse Model of Experimental Antigen-Induced Encephalomyelitis

Multiple sclerosis (MS) is a chronic, inflammatory, autoimmune disease of the central nervous system (CNS) which is associated with lower life expectancy and disability. The experimental antigen-induced encephalomyelitis (EAE) in mice is a useful animal model of MS, which allows exploring the etiopa...

Descripción completa

Detalles Bibliográficos
Autores principales: Stepanovska, Bisera, Zivkovic, Aleksandra, Enzmann, Gaby, Tietz, Silvia, Homann, Thomas, Kleuser, Burkhard, Engelhardt, Britta, Stark, Holger, Huwiler, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555234/
https://www.ncbi.nlm.nih.gov/pubmed/32899717
http://dx.doi.org/10.3390/ijms21186463