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Morpholino Analogues of Fingolimod as Novel and Selective S1P(1) Ligands with In Vivo Efficacy in a Mouse Model of Experimental Antigen-Induced Encephalomyelitis
Multiple sclerosis (MS) is a chronic, inflammatory, autoimmune disease of the central nervous system (CNS) which is associated with lower life expectancy and disability. The experimental antigen-induced encephalomyelitis (EAE) in mice is a useful animal model of MS, which allows exploring the etiopa...
Autores principales: | Stepanovska, Bisera, Zivkovic, Aleksandra, Enzmann, Gaby, Tietz, Silvia, Homann, Thomas, Kleuser, Burkhard, Engelhardt, Britta, Stark, Holger, Huwiler, Andrea |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555234/ https://www.ncbi.nlm.nih.gov/pubmed/32899717 http://dx.doi.org/10.3390/ijms21186463 |
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