Using Ex Vivo Porcine Jejunum to Identify Membrane Transporter Substrates: A Screening Tool for Early—Stage Drug Development

Robust, predictive ex vivo/in vitro models to study intestinal drug absorption by passive and active transport mechanisms are scarce. Membrane transporters can significantly impact drug uptake and transporter-mediated drug–drug interactions can play a pivotal role in determining the drug safety prof...

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Detalles Bibliográficos
Autores principales: Arnold, Yvonne E., Kalia, Yogeshvar N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555276/
https://www.ncbi.nlm.nih.gov/pubmed/32927779
http://dx.doi.org/10.3390/biomedicines8090340

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555276/
https://www.ncbi.nlm.nih.gov/pubmed/32927779
http://dx.doi.org/10.3390/biomedicines8090340

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