Downregulation of CDC20 Increases Radiosensitivity through Mcl-1/p-Chk1-Mediated DNA Damage and Apoptosis in Tumor Cells

Radiotherapy is an important modality for the local control of human cancers, but the radioresistance induced by aberrant apoptotic signaling is a hallmark of cancers. Restoring the aberrant apoptotic pathways is an emerging strategy for cancer radiotherapy. In this study, we determined that targeti...

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Detalles Bibliográficos
Autores principales: Gao, Yang, Wen, Pengbo, Chen, Bin, Hu, Guanshuo, Wu, Lijun, Xu, An, Zhao, Guoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555290/
https://www.ncbi.nlm.nih.gov/pubmed/32932732
http://dx.doi.org/10.3390/ijms21186692

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555290/
https://www.ncbi.nlm.nih.gov/pubmed/32932732
http://dx.doi.org/10.3390/ijms21186692

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