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STIM1 Deficiency Leads to Specific Down-Regulation of ITPR3 in SH-SY5Y Cells

STIM1 is an endoplasmic reticulum (ER) protein that modulates the activity of a number of Ca(2+) transport systems. By direct physical interaction with ORAI1, a plasma membrane Ca(2+) channel, STIM1 activates the I(CRAC) current, whereas the binding with the voltage-operated Ca(2+) channel Ca(V)1.2...

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Detalles Bibliográficos
Autores principales: Pascual-Caro, Carlos, Orantos-Aguilera, Yolanda, Sanchez-Lopez, Irene, de Juan-Sanz, Jaime, Parys, Jan B., Area-Gomez, Estela, Pozo-Guisado, Eulalia, Martin-Romero, Francisco Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555297/
https://www.ncbi.nlm.nih.gov/pubmed/32916960
http://dx.doi.org/10.3390/ijms21186598