Evaluating the Genotoxic and Cytotoxic Effects of Thymidine Analogs, 5-Ethynyl-2′-Deoxyuridine and 5-Bromo-2′-Deoxyurdine to Mammalian Cells

BrdU (bromodeoxyuridine) and EdU (ethynyldeoxyuridine) have been largely utilized as the means of monitoring DNA replication and cellular division. Although BrdU induces gene and chromosomal mutations and induces sensitization to photons, EdU‘s effects have not been extensively studied yet. Therefor...

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Detalles Bibliográficos
Autores principales: Haskins, Jeremy S., Su, Cathy, Maeda, Junko, Walsh, Kade D., Haskins, Alexis H., Allum, Allison J., Froning, Coral E., Kato, Takamitsu A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555307/
https://www.ncbi.nlm.nih.gov/pubmed/32927807
http://dx.doi.org/10.3390/ijms21186631

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555307/
https://www.ncbi.nlm.nih.gov/pubmed/32927807
http://dx.doi.org/10.3390/ijms21186631

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