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In Silico Identification and Biological Evaluation of Antioxidant Food Components Endowed with Human Carbonic Anhydrase IX and XII Inhibition

The tumor-associated isoenzymes hCA IX and hCA XII catalyze the hydration of carbon dioxide to bicarbonate and protons. These isoforms are highly overexpressed in many types of cancer, where they contribute to the acidification of the tumor environment, promoting tumor cell invasion and metastasis....

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Detalles Bibliográficos
Autores principales: Costa, Giosuè, Maruca, Annalisa, Rocca, Roberta, Ambrosio, Francesca Alessandra, Berrino, Emanuela, Carta, Fabrizio, Mesiti, Francesco, Salatino, Alessandro, Lanzillotta, Delia, Trapasso, Francesco, Artese, Anna, Alcaro, Stefano, Supuran, Claudiu T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555330/
https://www.ncbi.nlm.nih.gov/pubmed/32825614
http://dx.doi.org/10.3390/antiox9090775