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Priming Is Dispensable for NLRP3 Inflammasome Activation in Human Monocytes In Vitro
Interleukin (IL)-18 and IL-1β are potent pro-inflammatory cytokines that contribute to inflammatory conditions such as rheumatoid arthritis and Alzheimer’s disease. They are produced as inactive precursors that are activated by large macromolecular complexes called inflammasomes upon sensing damage...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555430/ https://www.ncbi.nlm.nih.gov/pubmed/33101286 http://dx.doi.org/10.3389/fimmu.2020.565924 |