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Priming Is Dispensable for NLRP3 Inflammasome Activation in Human Monocytes In Vitro

Interleukin (IL)-18 and IL-1β are potent pro-inflammatory cytokines that contribute to inflammatory conditions such as rheumatoid arthritis and Alzheimer’s disease. They are produced as inactive precursors that are activated by large macromolecular complexes called inflammasomes upon sensing damage...

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Detalles Bibliográficos
Autores principales:	Gritsenko, Anna, Yu, Shi, Martin-Sanchez, Fatima, Diaz-del-Olmo, Ines, Nichols, Eva-Maria, Davis, Daniel M., Brough, David, Lopez-Castejon, Gloria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555430/ https://www.ncbi.nlm.nih.gov/pubmed/33101286 http://dx.doi.org/10.3389/fimmu.2020.565924

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