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Insight into Molecular Mechanism for Activin A-Induced Bone Morphogenetic Protein Signaling

Activins transduce the TGF-β pathway through a heteromeric signaling complex consisting of type I and type II receptors, and activins also inhibit bone morphogenetic protein (BMP) signaling mediated by type I receptor ALK2. Recent studies indicated that activin A cross-activates the BMP pathway thro...

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Detalles Bibliográficos
Autores principales: Xie, Chen, Jiang, Wenjuan, Lacroix, Jerome J., Luo, Yun, Hao, Jijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555472/
https://www.ncbi.nlm.nih.gov/pubmed/32899497
http://dx.doi.org/10.3390/ijms21186498