PIK3CA mutation enrichment and quantitation from blood and tissue

PIK3CA is one of the two most frequently mutated genes in breast cancers, occurring in 30–40% of cases. Four frequent ‘hotspot’ PIK3CA mutations (E542K, E545K, H1047R and H1047L) account for 80–90% of all PIK3CA mutations in human malignancies and represent predictive biomarkers. Here we describe a...

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Detalles Bibliográficos
Autores principales: Keraite, Ieva, Alvarez-Garcia, Virginia, Garcia-Murillas, Isaac, Beaney, Matthew, Turner, Nicholas C., Bartos, Clare, Oikonomidou, Olga, Kersaudy-Kerhoas, Maïwenn, Leslie, Nicholas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555501/
https://www.ncbi.nlm.nih.gov/pubmed/33051521
http://dx.doi.org/10.1038/s41598-020-74086-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555501/
https://www.ncbi.nlm.nih.gov/pubmed/33051521
http://dx.doi.org/10.1038/s41598-020-74086-w

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