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PAK4 methylation by the methyltransferase SETD6 attenuates cell adhesion

P21-activated kinase 4 (PAK4), a member of serine/threonine kinases family is over-expressed in numerous cancer tumors and is associated with oncogenic cell proliferation, migration and invasion. Our recent work demonstrated that the SET-domain containing protein 6 (SETD6) interacts with and methyla...

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Detalles Bibliográficos
Autores principales: Vershinin, Zlata, Feldman, Michal, Levy, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555502/
https://www.ncbi.nlm.nih.gov/pubmed/33051544
http://dx.doi.org/10.1038/s41598-020-74081-1