Suppression of G6PD induces the expression and bisecting GlcNAc-branched N-glycosylation of E-Cadherin to block epithelial-mesenchymal transition and lymphatic metastasis

BACKGROUND: As the rate-limit enzyme of the pentose phosphate pathway, glucose-6-phosphate dehydrogenase (G6PD) plays important roles in tumour progression, but the exact mechanism through which G6PD controls cancer metastasis remains unclear. METHODS: G6PD expression in resected oral squamous cell...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Yifei, Li, Qingxiang, Niu, Lixuan, Xu, Le, Guo, Yuxing, Wang, Lin, Guo, Chuanbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555552/
https://www.ncbi.nlm.nih.gov/pubmed/32719549
http://dx.doi.org/10.1038/s41416-020-1007-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555552/
https://www.ncbi.nlm.nih.gov/pubmed/32719549
http://dx.doi.org/10.1038/s41416-020-1007-3

Ejemplares similares