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Tauroursodeoxycholic Acid Protects Retinal Pigment Epithelial Cells from Oxidative Injury and Endoplasmic Reticulum Stress In Vitro

Retinal degeneration is characterized by the dysfunction of retinal cells. Oxidative and endoplasmic reticulum (ER) stress play an important role in the pathogenesis and progression of retinal degeneration. Tauroursodeoxycholic acid (TUDCA) has been demonstrated to have protective effects in in vitr...

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Detalles Bibliográficos
Autores principales: Alhasani, Reem Hasaballah, Almarhoun, Mohammad, Zhou, Xinzhi, Reilly, James, Patterson, Steven, Zeng, Zhihong, Shu, Xinhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555559/
https://www.ncbi.nlm.nih.gov/pubmed/32967221
http://dx.doi.org/10.3390/biomedicines8090367