Aryl Hydrocarbon Receptor (AHR) Ligands as Selective AHR Modulators (SAhRMs)

The aryl hydrocarbon receptor (AhR) was first identified as the intracellular protein that bound and mediated the toxic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD, dioxin) and dioxin-like compounds (DLCs). Subsequent studies show that the AhR plays an important role in maintaining cellular...

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Detalles Bibliográficos
Autores principales: Safe, Stephen, Jin, Un-ho, Park, Hyejin, Chapkin, Robert S., Jayaraman, Arul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555580/
https://www.ncbi.nlm.nih.gov/pubmed/32932962
http://dx.doi.org/10.3390/ijms21186654