Simvastatin Impairs Glucose Homeostasis in Mice Depending on PGC-1α Skeletal Muscle Expression

Several studies showed an increased risk for diabetes with statin treatment. PGC-1α is an important regulator of muscle energy metabolism and mitochondrial biogenesis. Since statins impair skeletal muscle PGC-1α expression and reduced PGC-1α expression has been observed in diabetic patients, we inve...

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Detalles Bibliográficos
Autores principales: Panajatovic, Miljenko Valentin, Singh, François, Krähenbühl, Stephan, Bouitbir, Jamal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555587/
https://www.ncbi.nlm.nih.gov/pubmed/32942550
http://dx.doi.org/10.3390/biomedicines8090351

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555587/
https://www.ncbi.nlm.nih.gov/pubmed/32942550
http://dx.doi.org/10.3390/biomedicines8090351

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