Electrophile-Induced Conformational Switch of the Human TRPA1 Ion Channel Detected by Mass Spectrometry

The human Transient Receptor Potential A1 (hTRPA1) ion channel, also known as the wasabi receptor, acts as a biosensor of various potentially harmful stimuli. It is activated by a wide range of chemicals, including the electrophilic compound N-methylmaleimide (NMM), but the mechanism of activation i...

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Detalles Bibliográficos
Autores principales: Moparthi, Lavanya, Kjellström, Sven, Kjellbom, Per, Filipovic, Milos R., Zygmunt, Peter M., Johanson, Urban
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555621/
https://www.ncbi.nlm.nih.gov/pubmed/32933054
http://dx.doi.org/10.3390/ijms21186667

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555621/
https://www.ncbi.nlm.nih.gov/pubmed/32933054
http://dx.doi.org/10.3390/ijms21186667

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