Cerebral Vasodilator Property of Poly(ADP-Ribose) Polymerase Inhibitor (PJ34) in the Neonatal and Adult Mouse Is Mediated by the Nitric Oxide Pathway

The poly(ADP-ribose) polymerase (PARP) inhibitor PJ34 has been reported to improve endothelial dysfunction in the peripheral system. We addressed the role of PJ34 on the vascular tone and vasoreactivity during development in the mouse brain. Blood flows were measured in the basilar trunk using ultra...

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Detalles Bibliográficos
Autores principales: Bonnin, Philippe, Charriaut-Marlangue, Christiane, Pansiot, Julien, Boutigny, Alexandre, Launay, Jean-Marie, Besson, Valérie C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555622/
https://www.ncbi.nlm.nih.gov/pubmed/32911782
http://dx.doi.org/10.3390/ijms21186569

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555622/
https://www.ncbi.nlm.nih.gov/pubmed/32911782
http://dx.doi.org/10.3390/ijms21186569

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