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4-Acetylantroquinonol B Inhibits Osteoclastogenesis by Inhibiting the Autophagy Pathway in a Simulated Microgravity Model

Astronauts suffer from 1–2% bone loss per month during space missions. Targeting osteoclast differentiation has been regarded as a promising strategy to prevent osteoporosis in microgravity (μXg). 4-acetylantroquinonol B (4-AAQB), a ubiquinone from Antrodia cinnamomea, has shown anti-inflammatory an...

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Detalles Bibliográficos
Autores principales: Wu, Chia-Hsin, Ou, Ching-Huei, Yen, I-Chuan, Lee, Shih-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555662/
https://www.ncbi.nlm.nih.gov/pubmed/32971944
http://dx.doi.org/10.3390/ijms21186971