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Clinical Aspects and Current Therapeutic Approaches for FOP
Fibrodysplasia ossificans progressiva (FOP) is an extremely rare heritable disorder of connective tissues characterized by progressive heterotopic ossification in various skeletal sites. It is caused by gain-of-function mutations in the gene encoding activin A receptor type I (ACVR1)/activin-like ki...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555688/ https://www.ncbi.nlm.nih.gov/pubmed/32887348 http://dx.doi.org/10.3390/biomedicines8090325 |