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Clinical Aspects and Current Therapeutic Approaches for FOP

Fibrodysplasia ossificans progressiva (FOP) is an extremely rare heritable disorder of connective tissues characterized by progressive heterotopic ossification in various skeletal sites. It is caused by gain-of-function mutations in the gene encoding activin A receptor type I (ACVR1)/activin-like ki...

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Detalles Bibliográficos
Autor principal: Kitoh, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555688/
https://www.ncbi.nlm.nih.gov/pubmed/32887348
http://dx.doi.org/10.3390/biomedicines8090325