Hippuric Acid Promotes Renal Fibrosis by Disrupting Redox Homeostasis via Facilitation of NRF2–KEAP1–CUL3 Interactions in Chronic Kidney Disease

Chronic kidney disease (CKD) is characterized by the accumulation of protein-bound uremic toxins (PBUTs), which play a pathophysiological role in renal fibrosis (a common pathological process resulting in CKD progression). Accumulation of the PBUT hippuric acid (HA) is positively correlated with dis...

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Detalles Bibliográficos
Autores principales: Sun, Bowen, Wang, Xifan, Liu, Xiaoxue, Wang, Longjiao, Ren, Fazheng, Wang, Xiaoyu, Leng, Xiaojing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555723/
https://www.ncbi.nlm.nih.gov/pubmed/32854194
http://dx.doi.org/10.3390/antiox9090783

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555723/
https://www.ncbi.nlm.nih.gov/pubmed/32854194
http://dx.doi.org/10.3390/antiox9090783

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