Development and Technical Validation of an Immunoassay for the Detection of APP(669–711) (Aβ(−3–40)) in Biological Samples

The ratio of amyloid precursor protein (APP)(669–711) (Aβ(−3–40))/Aβ(1–42) in blood plasma was reported to represent a novel Alzheimer’s disease biomarker. Here, we describe the characterization of two antibodies against the N-terminus of Aβ(−3–x) and the development and “fit-for-purpose” technical...

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Detalles Bibliográficos
Autores principales: Klafki, Hans W., Rieper, Petra, Matzen, Anja, Zampar, Silvia, Wirths, Oliver, Vogelgsang, Jonathan, Osterloh, Dirk, Rohdenburg, Lara, Oberstein, Timo J., Jahn, Olaf, Beyer, Isaak, Lachmann, Ingolf, Knölker, Hans-Joachim, Wiltfang, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555726/
https://www.ncbi.nlm.nih.gov/pubmed/32911706
http://dx.doi.org/10.3390/ijms21186564

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555726/
https://www.ncbi.nlm.nih.gov/pubmed/32911706
http://dx.doi.org/10.3390/ijms21186564

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