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Development and Technical Validation of an Immunoassay for the Detection of APP(669–711) (Aβ(−3–40)) in Biological Samples
The ratio of amyloid precursor protein (APP)(669–711) (Aβ(−3–40))/Aβ(1–42) in blood plasma was reported to represent a novel Alzheimer’s disease biomarker. Here, we describe the characterization of two antibodies against the N-terminus of Aβ(−3–x) and the development and “fit-for-purpose” technical...
| Autores principales: | , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555726/ https://www.ncbi.nlm.nih.gov/pubmed/32911706 http://dx.doi.org/10.3390/ijms21186564 |