miR-29a Modulates GSK3β/SIRT1-Linked Mitochondrial Proteostatic Stress to Ameliorate Mouse Non-Alcoholic Steatohepatitis

MicroRNA-29a (miR-29a) has been shown to ameliorate hepatocellular damage, such as in the context of non-alcoholic fatty liver disease (NAFLD), steatohepatitis (NASH), and cholestatic injury. However, the mechanism mediating the hepatoprotective effect of miR-29a in diet-induced NASH remains elusive...

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Detalles Bibliográficos
Autores principales: Yang, Ya-Ling, Wang, Pei-Wen, Wang, Feng-Sheng, Lin, Hung-Yu, Huang, Ying-Hsien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555728/
https://www.ncbi.nlm.nih.gov/pubmed/32961796
http://dx.doi.org/10.3390/ijms21186884

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555728/
https://www.ncbi.nlm.nih.gov/pubmed/32961796
http://dx.doi.org/10.3390/ijms21186884

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