Interaction Modes of Microsomal Cytochrome P450s with Its Reductase and the Role of Substrate Binding

The activity of microsomal cytochromes P450 (CYP) is strictly dependent on the supply of electrons provided by NADPH cytochrome P450 oxidoreductase (CPR). The variant nature of the isoform-specific proximal interface of microsomal CYPs implies that the interacting interface between the two proteins...

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Detalles Bibliográficos
Autores principales: Esteves, Francisco, Urban, Philippe, Rueff, José, Truan, Gilles, Kranendonk, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555755/
https://www.ncbi.nlm.nih.gov/pubmed/32933097
http://dx.doi.org/10.3390/ijms21186669

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555755/
https://www.ncbi.nlm.nih.gov/pubmed/32933097
http://dx.doi.org/10.3390/ijms21186669

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