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Interaction Modes of Microsomal Cytochrome P450s with Its Reductase and the Role of Substrate Binding
The activity of microsomal cytochromes P450 (CYP) is strictly dependent on the supply of electrons provided by NADPH cytochrome P450 oxidoreductase (CPR). The variant nature of the isoform-specific proximal interface of microsomal CYPs implies that the interacting interface between the two proteins...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555755/ https://www.ncbi.nlm.nih.gov/pubmed/32933097 http://dx.doi.org/10.3390/ijms21186669 |