Pathogenic Mechanisms of Myeloma Bone Disease and Possible Roles for NRF2

Osteolytic bone lesions are one of the central features of multiple myeloma (MM) and lead to bone pain, fractures, decreased quality of life, and decreased survival. Dysfunction of the osteoclast (OC)/osteoblast (OB) axis plays a key role in the development of myeloma-associated osteolytic lesions....

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Detalles Bibliográficos
Autores principales: Yen, Chia-Hung, Hsu, Chin-Mu, Hsiao, Samuel Yien, Hsiao, Hui-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555756/
https://www.ncbi.nlm.nih.gov/pubmed/32937821
http://dx.doi.org/10.3390/ijms21186723

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555756/
https://www.ncbi.nlm.nih.gov/pubmed/32937821
http://dx.doi.org/10.3390/ijms21186723

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