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The Role of Smoothened in Cancer

Smoothened (SMO) belongs to the Hedgehog (HH) signaling pathway, which regulates cell growth, migration, invasion and stem cells in cancer. The HH signaling pathway includes both canonical and noncanonical pathways. The canonical HH pathway functions through major HH molecules such as HH ligands, PT...

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Detalles Bibliográficos
Autores principales: Jeng, Kuo-Shyang, Sheen, I-Shyan, Leu, Chuen-Miin, Tseng, Ping-Hui, Chang, Chiung-Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555769/
https://www.ncbi.nlm.nih.gov/pubmed/32962123
http://dx.doi.org/10.3390/ijms21186863