HSPA1L Enhances Cancer Stem Cell-Like Properties by Activating IGF1Rβ and Regulating β-Catenin Transcription

Studies have shown that cancer stem cells (CSCs) are involved in resistance and metastasis of cancer; thus, therapies targeting CSCs have been proposed. Here, we report that heat shock 70-kDa protein 1-like (HSPA1L) is partly involved in enhancing epithelial–mesenchymal transition (EMT) and CSC-like...

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Detalles Bibliográficos
Autores principales: Choi, Soo-Im, Lee, Jei-Ha, Kim, Rae-Kwon, Jung, Uhee, Kahm, Yeon-Jee, Cho, Eun-Wie, Kim, In-Gyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555772/
https://www.ncbi.nlm.nih.gov/pubmed/32971893
http://dx.doi.org/10.3390/ijms21186957

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555772/
https://www.ncbi.nlm.nih.gov/pubmed/32971893
http://dx.doi.org/10.3390/ijms21186957

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